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1

High-Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling during Successful Immune-Checkpoint Cancer Therapy

Gubin, Matthew M., Esaulova, Ekaterina, Ward, Jeffrey P., Malkova, Olga N., Runci, Daniele, Wong, Pamela, Noguchi, Takuro, Arthur, Cora D., Meng, Wei, Alspach, Elise, Medrano, Ruan F.V., Fronick, Catr

Journal:

Year:

2018

Language:

english

File:

PDF, 913 KB

english, 2018

2

CpG Island Hypermethylation Mediated by DNMT3A Is a Consequence of AML Progression

Spencer, David H., Russler-Germain, David A., Ketkar, Shamika, Helton, Nichole M., Lamprecht, Tamara L., Fulton, Robert S., Fronick, Catrina C., O’Laughlin, Michelle, Heath, Sharon E., Shinawi, Marwan

Journal:

Year:

2017

Language:

english

File:

PDF, 21.76 MB

english, 2017

3

A multiple myeloma-specific capture sequencing platform discovers novel translocations and frequent, risk-associated point mutations in IGLL5

White, Brian S., Lanc, Irena, O’Neal, Julie, Gupta, Harshath, Fulton, Robert S., Schmidt, Heather, Fronick, Catrina, Belter, Edward A., Fiala, Mark, King, Justin, Ahmann, Greg J., DeRome, Mary, Mardis

Journal:

Blood Cancer Journal

Year:

2018

Language:

english

File:

PDF, 1.33 MB

english, 2018

4

Zoo-FISH delineates conserved chromosomal segments in horse and man

Terje Raudsepp, Lutz Frönicke, Harry Scherthan, Ingemar Gustavsson, Bhanu P. Chowdhary

Journal:

Chromosome Research

Year:

1996

Language:

english

File:

PDF, 3.89 MB

english, 1996

5

Comparative chromosome painting defines the high rate of karyotype changes between pigs and bovids

Lutz Frönicke, Johannes Wienberg

Journal:

Mammalian Genome

Year:

2001

Language:

english

File:

PDF, 2.50 MB

english, 2001

6

Assignment of the porcine nuclear factor I/CTF(NFI/CTF)gene to Chromosome 2q12-13 by FISH

Lutz Frönicke, Harry Scherthan

Journal:

Mammalian Genome

Year:

1997

Language:

english

File:

PDF, 1.09 MB

english, 1997

7

Chromosomal homeologies between human, harbor seal (Phoca vitulina) and the putative ancestral carnivore karyotype revealed by Zoo-FISH

Lutz Frönicke, Jutta Müller-Navia, Konstantinos Romanakis, Harry Scherthan

Journal:

Year:

1997

Language:

english

File:

PDF, 218 KB

english, 1997

8

Comparative chromosome painting discloses homologous segments in distantly related mammals

Scherthan, Harry, Cremer, Thomas, Arnason, Ulfur, Weier, Heinz-Ulrich, Lima-de-Faria, Antonio, Frönicke, Lutz

Journal:

Nature Genetics

Year:

1994

File:

PDF, 767 KB

1994

9

Comparative analysis of the cattle and human genomes: detection of ZOO-FISH and gene mapping-based chromosomal homologies

B. P. Chowdhary, L. Frönicke, I. Gustavsson, H. Scherthan

Journal:

Mammalian Genome

Year:

1996

Language:

english

File:

PDF, 3.24 MB

english, 1996

10

A comparative map of the porcine and human genomes demonstrates ZOO-FISH and gene mapping-based chromosomal homologies

L. Frönicke, B. P. Chowdhary, H. Scherthan, I. Gustavsson

Journal:

Mammalian Genome

Year:

1996

Language:

english

File:

PDF, 3.00 MB

english, 1996

11

Modification of a commercially available DNA sequencer to increase sample throughput

Stuebe, E.T., Steward, J.Q., Chinwalia, A., Cook, L.L., Cook, M., Fronick, B., Miller, K., Mullen, M.K., O'Brien, D., Panussis, D.A., Pohl, C., Snider, J.E., Strong, J., Williams, D., Wilson, R.K., Ti

Journal:

IEEE Engineering in Medicine and Biology Magazine

Year:

2000

Language:

english

File:

PDF, 559 KB

english, 2000

12

High-throughput comparison of gene fitness among related bacteria

Canals, Rocio, Xia, Xiao-Qin, Fronick, Catrina, Clifton, Sandra W, Ahmer, Brian MM, Andrews-Polymenis, Helene L, Porwollik, Steffen, McClelland, Michael

Journal:

Year:

2012

Language:

english

File:

PDF, 263 KB

english, 2012

13

Subtelomeric CTCF and cohesin binding site organization using improved subtelomere assemblies and a novel annotation pipeline

Stong, N., Deng, Z., Gupta, R., Hu, S., Paul, S., Weiner, A. K., Eichler, E. E., Graves, T., Fronick, C. C., Courtney, L., Wilson, R. K., Lieberman, P. M., Davuluri, R. V., Riethman, H.

Journal:

Genome Research

Year:

2014

Language:

english

File:

PDF, 1.09 MB

english, 2014

14

Functional Heterogeneity of Genetically Defined Subclones in Acute Myeloid Leukemia

Klco, Jeffery M., Spencer, David H., Miller, Christopher A., Griffith, Malachi, Lamprecht, Tamara L., O’Laughlin, Michelle, Fronick, Catrina, Magrini, Vincent, Demeter, Ryan T., Fulton, Robert S., Ead

Journal:

Year:

2014

Language:

english

File:

PDF, 3.25 MB

english, 2014

15

Towards the Delineation of the Ancestral Eutherian Genome Organization: Comparative Genome Maps of Human and the African Elephant (Loxodonta africana) Generated by Chromosome Painting

Lutz Frönicke, Johannes Wienberg, Gary Stone, Lisa Adams and Roscoe Stanyon

Journal:

Proceedings Biological Sciences

Year:

2003

Language:

english

File:

PDF, 1.98 MB

english, 2003

16

Identification of a rare coding variant in complement 3 associated with age-related macular degeneration

Zhan, Xiaowei, Larson, David E, Wang, Chaolong, Koboldt, Daniel C, Sergeev, Yuri V, Fulton, Robert S, Fulton, Lucinda L, Fronick, Catrina C, Branham, Kari E, Bragg-Gresham, Jennifer, Jun, Goo, Hu, You

Journal:

Nature Genetics

Year:

2013

Language:

english

File:

PDF, 578 KB

english, 2013

17

Epigenomic analysis of the HOX gene loci reveals mechanisms that may control canonical expression patterns in AML and normal hematopoietic cells

Spencer, D H, Young, M A, Lamprecht, T L, Helton, N M, Fulton, R, O'Laughlin, M, Fronick, C, Magrini, V, Demeter, R T, Miller, C A, Klco, J M, Wilson, R K, Ley, T J

Journal:

Year:

2015

Language:

english

File:

PDF, 8.19 MB

english, 2015

18

Sequencing human-gibbon breakpoints of synteny reveals mosaic new insertions at rearrangement sites

Girirajan, S., Chen, L., Graves, T., Marques-Bonet, T., Ventura, M., Fronick, C., Fulton, L., Rocchi, M., Fulton, R. S., Wilson, R. K., Mardis, E. R., Eichler, E. E.

Journal:

Genome Research

Year:

2008

Language:

english

File:

PDF, 2.71 MB

english, 2008

19

Towards the delineation of the ancestral eutherian genome organization: comparative genome maps of human and the African elephant (Loxodonta africana) generated by chromosome painting

Fronicke, L., Wienberg, J., Stone, G., Adams, L., Stanyon, R.

Journal:

Proceedings Biological Sciences

Year:

2003

Language:

english

File:

PDF, 490 KB

english, 2003

20

Correction for Fronicke et al., Towards the delineation of the ancestral eutherian genome organization: comparative genome maps of human and the African elephant (Loxodonta africana) generated by chromosome painting

Fronicke, L., Wienberg, J., Stone, G., Adams, L., Stanyon, R.

Journal:

Proceedings Biological Sciences

Year:

2003

Language:

english

File:

PDF, 68 KB

english, 2003

21

The Physarum polycephalum Genome Reveals Extensive Use of Prokaryotic Two-component and Metazoan-type Tyrosine Kinase Signaling

Schaap, Pauline, Barrantes, Israel, Minx, Pat, Sasaki, Narie, Anderson, Roger W., Bénard, Marianne, Biggar, Kyle K., Buchler, Nicolas E., Bundschuh, Ralf, Chen, Xiao, Fronick, Catrina, Fulton, Lucinda

Journal:

Genome Biology and Evolution

Year:

2015

Language:

english

File:

PDF, 4.28 MB

english, 2015

22

Targeted sequencing informs the evaluation of normal karyotype cytopenic patients for low-grade myelodysplastic syndrome

Duncavage, E J, O’Brien, J, Vij, K, Miller, C A, Chang, G S, Shao, J, Jacoby, M A, Heath, S, Janke, M R, Elliott, K, Fulton, R S, Fronick, C, O'Laughlin, M, Westervelt, P, Ley, T J, Wilson, R K, Walte

Journal:

Year:

2016

Language:

english

File:

PDF, 1.16 MB

english, 2016

23

Genomic analysis of germ line and somatic variants in familial myelodysplasia/acute myeloid leukemia

Churpek, J. E., Pyrtel, K., Kanchi, K.-L., Shao, J., Koboldt, D., Miller, C. A., Shen, D., Fulton, R., O'Laughlin, M., Fronick, C., Pusic, I., Uy, G. L., Braunstein, E. M., Levis, M., Ross, J., Elliot

Journal:

Year:

2015

Language:

english

File:

PDF, 915 KB

english, 2015

24

Dynamic changes in the clonal structure of MDS and AML in response to epigenetic therapy

Uy, G L, Duncavage, E J, Chang, G S, Jacoby, M A, Miller, C A, Shao, J, Heath, S, Elliott, K, Reinick, T, Fulton, R S, Fronick, C C, O'Laughlin, M, Ganel, L, Abboud, C N, Cashen, A F, DiPersio, J F, W

Journal:

Year:

2016

Language:

english

File:

PDF, 2.96 MB

english, 2016

25

TP53 and Decitabine in Acute Myeloid Leukemia and Myelodysplastic Syndromes

Welch, John S., Petti, Allegra A., Miller, Christopher A., Fronick, Catrina C., O’Laughlin, Michelle, Fulton, Robert S., Wilson, Richard K., Baty, Jack D., Duncavage, Eric J., Tandon, Bevan, Lee, Yi-S

Journal:

New England Journal of Medicine

Year:

2016

Language:

english

File:

PDF, 552 KB

english, 2016

26

Recurrent somatic mutations affecting B-cell receptor signaling pathway genes in follicular lymphoma

Krysiak, Kilannin, Gomez, Felicia, White, Brian S., Matlock, Matthew, Miller, Christopher A., Trani, Lee, Fronick, Catrina C., Fulton, Robert S., Kreisel, Friederike, Cashen, Amanda F., Carson, Kennet

Journal:

Year:

2017

Language:

english

File:

PDF, 845 KB

english, 2017

27

Mutant U2AF1-expressing cells are sensitive to pharmacological modulation of the spliceosome

Shirai, Cara Lunn, White, Brian S., Tripathi, Manorama, Tapia, Roberto, Ley, James N., Ndonwi, Matthew, Kim, Sanghyun, Shao, Jin, Carver, Alexa, Saez, Borja, Fulton, Robert S., Fronick, Catrina, O’Lau

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 1.28 MB

english, 2017

28

Mutational landscape and response are conserved in peripheral blood of AML and MDS patients during decitabine therapy

Duncavage, Eric J., Uy, Geoffrey L., Petti, Allegra A., Miller, Christopher A., Lee, Yi-Shan, Tandon, Bevan, Gao, Feng, Fronick, Catrina C., O’Laughlin, Michelle, Fulton, Robert S., Wilson, Richard K.

Journal:

Year:

2017

Language:

english

File:

PDF, 146 KB

english, 2017

29

Genetic Heterogeneity of Induced Pluripotent Stem Cells: Results from 24 Clones Derived from a Single C57BL/6 Mouse

Li, Cheng, Klco, Jeffery M., Helton, Nichole M., George, Daniel R., Mudd, Jacqueline L., Miller, Christopher A., Lu, Charles, Fulton, Robert, O'Laughlin, Michelle, Fronick, Catrina, Wilson, Richard K.

Journal:

Year:

2015

Language:

english

File:

PDF, 9.62 MB

english, 2015

30

Mutation Clearance after Transplantation for Myelodysplastic Syndrome

Duncavage, Eric J., Jacoby, Meagan A., Chang, Gue Su, Miller, Christopher A., Edwin, Natasha, Shao, Jin, Elliott, Kevin, Robinson, Joshua, Abel, Haley, Fulton, Robert S., Fronick, Catrina C., O’Laughl

Journal:

New England Journal of Medicine

Year:

2018

Language:

english

File:

PDF, 402 KB

english, 2018

31

High-Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling during Successful Immune-Checkpoint Cancer Therapy

Gubin, Matthew M., Esaulova, Ekaterina, Ward, Jeffrey P., Malkova, Olga N., Runci, Daniele, Wong, Pamela, Noguchi, Takuro, Arthur, Cora D., Meng, Wei, Alspach, Elise, Medrano, Ruan F.V., Fronick, Catr

Journal:

Year:

2018

Language:

english

File:

PDF, 14.53 MB

english, 2018

32

Immune Escape of Relapsed AML Cells after Allogeneic Transplantation

Christopher, Matthew J., Petti, Allegra A., Rettig, Michael P., Miller, Christopher A., Chendamarai, Ezhilarasi, Duncavage, Eric J., Klco, Jeffery M., Helton, Nicole M., O’Laughlin, Michelle, Fronick,

Journal:

New England Journal of Medicine

Year:

2018

Language:

english

File:

PDF, 1.02 MB

english, 2018

33

[Methods in Enzymology] High-Density Sequencing Applications in Microbial Molecular Genetics Volume 612 || Toward Cell Type-Specific In Vivo Dual RNA-Seq

Frönicke, Lutz

Year:

2018

Language:

english

File:

PDF, 1.22 MB

english, 2018

34

A general approach for detecting expressed mutations in AML cells using single cell RNA-sequencing

Petti, Allegra A., Williams, Stephen R., Miller, Christopher A., Fiddes, Ian T., Srivatsan, Sridhar N., Chen, David Y., Fronick, Catrina C., Fulton, Robert S., Church, Deanna M., Ley, Timothy J.

Journal:

Nature Communications

Year:

2019

Language:

english

File:

PDF, 5.66 MB

english, 2019

35

Remethylation of Dnmt3a â/â hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing

Ketkar, Shamika, Verdoni, Angela M., Smith, Amanda M., Bangert, Celia V., Leight, Elizabeth R., Chen, David Y., Brune, Meryl K., Helton, Nichole M., Hoock, Mieke, George, Daniel R., Fronick, Catrina,

Journal:

Proceedings of the National Academy of Sciences

Year:

2020

File:

PDF, 6.50 MB

2020

36

Harnessing Expressed Single Nucleotide Variation and Single Cell RNA Sequencing To Define Immune Cell Chimerism in the Rejecting Kidney Transplant

Malone, Andrew F., Wu, Haojia, Fronick, Catrina, Fulton, Robert, Gaut, Joseph P., Humphreys, Benjamin D.

Journal:

Journal of the American Society of Nephrology

Year:

2020

File:

PDF, 1.30 MB

2020

37

TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy

Molgora, Martina, Esaulova, Ekaterina, Vermi, William, Hou, Jinchao, Chen, Yun, Luo, Jingqin, Brioschi, Simone, Bugatti, Mattia, Omodei, Andrea Salvatore, Ricci, Biancamaria, Fronick, Catrina, Panda,

Journal:

Year:

2020

File:

PDF, 11.51 MB

2020

38

Rapid and extraction-free detection of SARS-CoV-2 from saliva by colorimetric reverse-transcription loop-mediated isothermal amplification

Lalli, Matthew A, Langmade, S Joshua, Chen, Xuhua, Fronick, Catrina C, Sawyer, Christopher S, Burcea, Lauren C, Wilkinson, Michael N, Fulton, Robert S, Heinz, Michael, Buchser, William J, Head, Richar

Journal:

Clinical Chemistry

Year:

2020

File:

PDF, 2.17 MB

2020

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